diff --git a/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.cpp b/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.cpp
index c8415947..b98740d3 100644
--- a/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.cpp
+++ b/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.cpp
@@ -720,16 +720,18 @@ namespace Bloom::DebugToolDrivers::Protocols::CmsisDap::Edbg::Avr
         return this->writeMemory(avr8MemoryType, startAddress, buffer);
     }
 
-    void EdbgAvr8Interface::eraseProgramMemorySection(ProgramMemorySection section) {
-        if (this->configVariant != Avr8ConfigVariant::XMEGA) {
-            throw Exception("AVR8 erase command not supported for non-XMEGA config variants.");
+    void EdbgAvr8Interface::eraseProgramMemory(std::optional<Avr8Bit::ProgramMemorySection> section) {
+        if (this->configVariant == Avr8ConfigVariant::DEBUG_WIRE) {
+            throw Exception("AVR8 erase command not supported for debugWire config variant.");
         }
 
         auto response = this->edbgInterface.sendAvrCommandFrameAndWaitForResponseFrame(
             EraseMemory(
-                section == ProgramMemorySection::BOOT
-                    ? Avr8EraseMemoryMode::BOOT_SECTION
-                    : Avr8EraseMemoryMode::APPLICATION_SECTION
+                section.has_value()
+                    ? section == ProgramMemorySection::BOOT
+                        ? Avr8EraseMemoryMode::BOOT_SECTION
+                        : Avr8EraseMemoryMode::APPLICATION_SECTION
+                    : Avr8EraseMemoryMode::CHIP
             )
         );
 
diff --git a/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.hpp b/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.hpp
index 92e5fc52..d411bc53 100644
--- a/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.hpp
+++ b/src/DebugToolDrivers/Protocols/CMSIS-DAP/VendorSpecific/EDBG/AVR/EdbgAvr8Interface.hpp
@@ -243,11 +243,13 @@ namespace Bloom::DebugToolDrivers::Protocols::CmsisDap::Edbg::Avr
         ) override;
 
         /**
-         * Issues the "Erase" command to erase a particular section of program memory.
+         * Issues the "Erase" command to erase a particular section of program memory, or the entire chip.
          *
          * @param section
          */
-        void eraseProgramMemorySection(Targets::Microchip::Avr::Avr8Bit::ProgramMemorySection section) override;
+        void eraseProgramMemory(
+            std::optional<Targets::Microchip::Avr::Avr8Bit::ProgramMemorySection> section = std::nullopt
+        ) override;
 
         /**
          * Returns the current state of the target.
diff --git a/src/DebugToolDrivers/TargetInterfaces/Microchip/AVR/AVR8/Avr8DebugInterface.hpp b/src/DebugToolDrivers/TargetInterfaces/Microchip/AVR/AVR8/Avr8DebugInterface.hpp
index 37ced9d2..7f78f704 100644
--- a/src/DebugToolDrivers/TargetInterfaces/Microchip/AVR/AVR8/Avr8DebugInterface.hpp
+++ b/src/DebugToolDrivers/TargetInterfaces/Microchip/AVR/AVR8/Avr8DebugInterface.hpp
@@ -2,6 +2,7 @@
 
 #include <cstdint>
 #include <set>
+#include <optional>
 
 #include "src/Targets/Microchip/AVR/AVR8/Avr8TargetConfig.hpp"
 
@@ -196,11 +197,14 @@ namespace Bloom::DebugToolDrivers::TargetInterfaces::Microchip::Avr::Avr8
         ) = 0;
 
         /**
-         * Should erase a particular program memory section.
+         * Should erase the target's entire program memory, or a specific section where applicable.
          *
          * @param section
+         *  The section to erase, or std::nullopt to erase the entire program memory.
          */
-        virtual void eraseProgramMemorySection(Targets::Microchip::Avr::Avr8Bit::ProgramMemorySection section) = 0;
+        virtual void eraseProgramMemory(
+            std::optional<Targets::Microchip::Avr::Avr8Bit::ProgramMemorySection> section = std::nullopt
+        ) = 0;
 
         /**
          * Should obtain the current target state.
diff --git a/src/Targets/Microchip/AVR/AVR8/Avr8.cpp b/src/Targets/Microchip/AVR/AVR8/Avr8.cpp
index 0aaaf2d5..83536926 100644
--- a/src/Targets/Microchip/AVR/AVR8/Avr8.cpp
+++ b/src/Targets/Microchip/AVR/AVR8/Avr8.cpp
@@ -325,42 +325,48 @@ namespace Bloom::Targets::Microchip::Avr::Avr8Bit
     void Avr8::writeMemory(TargetMemoryType memoryType, std::uint32_t startAddress, const TargetMemoryBuffer& buffer) {
         if (
             memoryType == TargetMemoryType::FLASH && this->programmingSession.has_value()
-            && this->targetConfig->physicalInterface == PhysicalInterface::PDI
+            && this->targetConfig->physicalInterface != PhysicalInterface::DEBUG_WIRE
         ) {
-            // For PDI targets, we must erase the appropriate section before the first write.
-            const auto startSection = this->getProgramMemorySectionFromAddress(startAddress);
-            const auto endSection = this->getProgramMemorySectionFromAddress(
-                static_cast<std::uint32_t>(startAddress + buffer.size() - 1)
-            );
-
-            if (startSection != endSection) {
-                throw Exception(
-                    "Requested program memory write spans more than one section (APPLICATION and BOOT) - aborting."
+            if (this->targetConfig->physicalInterface == PhysicalInterface::PDI) {
+                const auto startSection = this->getProgramMemorySectionFromAddress(startAddress);
+                const auto endSection = this->getProgramMemorySectionFromAddress(
+                    static_cast<std::uint32_t>(startAddress + buffer.size() - 1)
                 );
-            }
 
-            if (
-                !this->programmingSession->applicationSectionErased
-                && (
-                    startSection == ProgramMemorySection::APPLICATION
-                    || endSection == ProgramMemorySection::APPLICATION
-                )
-            ) {
-                Logger::warning("Erasing program memory APPLICATION section, in preparation for writing.");
-                this->avr8DebugInterface->eraseProgramMemorySection(ProgramMemorySection::APPLICATION);
-                this->programmingSession->applicationSectionErased = true;
-            }
+                if (startSection != endSection) {
+                    throw Exception(
+                        "Requested program memory write spans more than one section (APPLICATION and BOOT) - aborting."
+                    );
+                }
 
-            if (
-                !this->programmingSession->bootSectionErased
+                if (
+                    !this->programmingSession->applicationSectionErased
+                    && (
+                        startSection == ProgramMemorySection::APPLICATION
+                        || endSection == ProgramMemorySection::APPLICATION
+                    )
+                ) {
+                    Logger::warning("Erasing program memory APPLICATION section, in preparation for programming.");
+                    this->avr8DebugInterface->eraseProgramMemory(ProgramMemorySection::APPLICATION);
+                    this->programmingSession->applicationSectionErased = true;
+                }
+
+                if (
+                    !this->programmingSession->bootSectionErased
                     && (
                         startSection == ProgramMemorySection::BOOT
                         || endSection == ProgramMemorySection::BOOT
                     )
-            ) {
-                Logger::warning("Erasing program memory BOOT section, in preparation for writing.");
-                this->avr8DebugInterface->eraseProgramMemorySection(ProgramMemorySection::BOOT);
-                this->programmingSession->bootSectionErased = true;
+                ) {
+                    Logger::warning("Erasing program memory BOOT section, in preparation for programming.");
+                    this->avr8DebugInterface->eraseProgramMemory(ProgramMemorySection::BOOT);
+                    this->programmingSession->bootSectionErased = true;
+                }
+
+            } else if (!this->programmingSession->chipErased) {
+                Logger::warning("Erasing entire chip, in preparation for programming.");
+                this->avr8DebugInterface->eraseProgramMemory();
+                this->programmingSession->chipErased = true;
             }
         }
 
@@ -962,7 +968,8 @@ namespace Bloom::Targets::Microchip::Avr::Avr8Bit
     }
 
     ProgramMemorySection Avr8::getProgramMemorySectionFromAddress(std::uint32_t address) {
-        return address >= this->targetParameters->bootSectionStartAddress.value()
+        return this->targetParameters->bootSectionStartAddress.has_value()
+            && address >= this->targetParameters->bootSectionStartAddress.value()
             ? ProgramMemorySection::BOOT
             : ProgramMemorySection::APPLICATION;
     }
diff --git a/src/Targets/Microchip/AVR/AVR8/ProgrammingSession.hpp b/src/Targets/Microchip/AVR/AVR8/ProgrammingSession.hpp
index ad81c5ad..3e76ee51 100644
--- a/src/Targets/Microchip/AVR/AVR8/ProgrammingSession.hpp
+++ b/src/Targets/Microchip/AVR/AVR8/ProgrammingSession.hpp
@@ -4,6 +4,7 @@ namespace Bloom::Targets::Microchip::Avr::Avr8Bit
 {
     struct ProgrammingSession
     {
+        bool chipErased = false;
         bool applicationSectionErased = false;
         bool bootSectionErased = false;
     };